Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells.

نویسندگان

  • Michael D Scott
  • Rinku Dutta
  • Manas K Haldar
  • Anil Wagh
  • Thomas R Gustad
  • Benedict Law
  • Daniel L Friesner
  • Sanku Mallik
چکیده

Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a post-translation level possibly due to their ability to interact with extracellular enzymes that are over-expressed in cancerous conditions.

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عنوان ژورنال:
  • The Analyst

دوره 137 23  شماره 

صفحات  -

تاریخ انتشار 2012